The cube on the left, which has one face shaded orange, is opened out into the net on the right. Which letter is on the face opposite the shaded face?

The row A B C D wraps round to form the four side faces, and the two squares attached to it on opposite sides of the row (the shaded one above, E below) become the top and the bottom: opposite faces. B, directly below the shaded square, is next to it on the cube.